Wise G J, Talluri G S, Marella V K
Division of Urology, Maimonides Medical Center, Brooklyn, New York, USA.
Urol Clin North Am. 1999 Nov;26(4):701-18, vii. doi: 10.1016/s0094-0143(05)70212-3.
There is an increasing pool of immunocompromised patients who are at an increased risk to fungi infections, which now cause 8% of nosocomial infections. Premature infants and elderly, transplant, and HIV patients are prime candidates for invasive fungal infections. The genitourinary system can be a source or target of disseminated fungal infection. Although candidal species are the most frequent pathogen, other species such as aspergila, cryptoccoccus have become major pathogens. "Environmental fungi," which include blastomyces, coccidioides and histoplasma, have become more aggressive in the vulnerable patient.
免疫功能低下的患者群体不断扩大,他们发生真菌感染的风险增加,真菌感染目前占医院感染的8%。早产儿、老年人、移植患者和艾滋病毒患者是侵袭性真菌感染的主要对象。泌尿生殖系统可能是播散性真菌感染的来源或靶器官。虽然念珠菌属是最常见的病原体,但其他菌种如曲霉菌、隐球菌也已成为主要病原体。包括芽生菌、球孢子菌和组织胞浆菌在内的“环境真菌”,在易感患者中变得更具侵袭性。