Weiss C, Willems S, Hoffmann M, Meinertz T
Department of Cardiology, University Hospital Eppendorf, Hamburg, Germany.
Pacing Clin Electrophysiol. 1999 Oct;22(10):1457-65. doi: 10.1111/j.1540-8159.1999.tb00349.x.
Induction of complete bidirectional conduction block via the posterior isthmus of the right atrium is introduced as a standard endpoint for catheter ablation of atrial flutter. The present study sought to investigate the impact of changes in P wave duration and morphology detected by the surface ECG during coronary sinus and posterolateral right atrial stimulation as a marker for conduction block. Morphology and duration changes of the paced P wave before and after radiofrequency catheter (RFC) ablation were estimated in 22 patients referred for ablation of atrial flutter. We looked for a morphology change of the terminal portion in the 12-lead ECG and an increment of P wave duration. In 16 of 22 patients in whom atrial flutter ablation resulted in a complete bidirectional block, the conduction block was unidirectional in 4 patients and conduction times remained unchanged in 2 patients. After induction of complete bidirectional block a change of the terminal portion of the P wave towards a more positive morphology in one or more inferior leads was detected in 14 (88%) of 16 patients during coronary sinus stimulation and in 15 (94%) of 16 patients during posterolateral right atrial stimulation. These changes were predominantly observed in the inferior leads. Positive morphology changes of the terminal P wave portion in the inferior leads indicating conduction block with a sensitivity of 86% and a specificity of 100% were observed. An increment of 10 ms or more in P wave duration indicates conduction block with a specificity of 100% and a sensitivity of 67%. There was a significantly larger increment of P wave duration during coronary sinus (CS) stimulation compared to posterolateral right atrial stimulation (38 +/- 21 vs 16 +/- 21 ms). The analysis of P wave duration and morphology in the inferior leads of the surface ECG is a reliable tool to assess the intraatrial conduction after atrial flutter ablation. Different conduction during coronary sinus and posterolateral right atrial pacing may cause a different P wave duration after ablation.
通过右心房后峡部诱发完全性双向传导阻滞被引入作为心房扑动导管消融的标准终点。本研究旨在探讨在冠状窦和右心房后外侧刺激期间,体表心电图检测到的P波持续时间和形态变化作为传导阻滞标志物的影响。对22例因心房扑动消融而就诊的患者,评估了射频导管(RFC)消融前后起搏P波的形态和持续时间变化。我们观察了12导联心电图终末部分的形态变化和P波持续时间的增加。在22例心房扑动消融导致完全性双向阻滞的患者中,16例患者的传导阻滞为单向性,4例患者传导时间未改变,2例患者传导时间保持不变。在诱发完全性双向阻滞后,16例患者中有14例(88%)在冠状窦刺激期间以及16例患者中有15例(94%)在右心房后外侧刺激期间,检测到P波终末部分在一个或多个下壁导联向更正向形态的变化。这些变化主要在下壁导联中观察到。观察到下壁导联中P波终末部分正向形态变化提示传导阻滞,敏感性为86%,特异性为100%。P波持续时间增加10 ms或更多提示传导阻滞,特异性为100%,敏感性为67%。与右心房后外侧刺激相比,冠状窦(CS)刺激期间P波持续时间的增加明显更大(38±21 vs 16±21 ms)。体表心电图下壁导联中P波持续时间和形态的分析是评估心房扑动消融后心房内传导的可靠工具。冠状窦和右心房后外侧起搏期间的不同传导可能导致消融后P波持续时间不同。