子宫颈癌淋巴结的冰冻切片
Frozen section of lymph nodes in uterine cervical carcinoma.
作者信息
Morice P, Sabourin J C, Castaigne D, Mercier S, Pautier P, Spatz A, Duvillard P, Michel G
机构信息
Department of Gynecologic Surgery, Institut Gustave Roussy, Villejuif, France.
出版信息
Clin Exp Pathol. 1999;47(5):223-6.
UNLABELLED
The aim of this study was to evaluate the accuracy of frozen section examination of lymph nodes in cervical cancer.
METHODS
This retrospective study was based on 55 patients with stage Ib or IIa invasive cervical carcinoma treated by surgery followed by irradiation. All patients underwent a pelvic lymphadenectomy with frozen section analysis of lymph nodes.
RESULTS
A total of 1249 nodes were removed (23 per patient) and 501 nodes (40%) were examined during the frozen section analysis. The sensitivity of frozen sections analysis in detecting metastatic nodes was 89%, its specificity and positive predictive value was 100% and its negative predictive value was 97%.
CONCLUSIONS
The frozen section diagnosis of pelvic nodes should be performed in patients with a small cervical carcinoma to avoid systematic para-aortic lymphadenectomy. This is an accurate procedure and should be carried out on obturator, external iliac and common iliac nodes.
未标注
本研究的目的是评估宫颈癌淋巴结冰冻切片检查的准确性。
方法
本回顾性研究基于55例接受手术加放疗的Ib期或IIa期浸润性宫颈癌患者。所有患者均接受盆腔淋巴结清扫术并对淋巴结进行冰冻切片分析。
结果
共切除1249个淋巴结（每位患者23个），其中501个淋巴结（40%）在冰冻切片分析时接受检查。冰冻切片分析检测转移淋巴结的敏感性为89%，特异性和阳性预测值为100%，阴性预测值为97%。
结论
对于小宫颈癌患者应进行盆腔淋巴结的冰冻切片诊断，以避免系统性主动脉旁淋巴结清扫术。这是一种准确的操作，应在闭孔、髂外和髂总淋巴结上进行。
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