Bandoh S, Fujita J, Fukunaga Y, Yokota K, Ueda Y, Okada H, Takahara J
First Department of Internal Medicine, Kagawa Medical University, Kita-gun, Japan.
Lung Cancer. 1999 Dec;26(3):195-8. doi: 10.1016/s0169-5002(99)00080-x.
A 66-year-old man who complained of cough and haemoptysis had a cavitary lesion with the meniscus sign in the right lower lung field on his chest X-ray and CT scan. He had smoked 40 cigarettes daily, for about 46 years. Initially, he was diagnosed with aspergilloma and given an antifungal agent. After 2 months, the cavitary lesion showed a slight irregularity of the inner border. The walls were irregularly thickened and were surrounded by infiltrative densities compared with the previous chest radiograph. Enlargement of right hilar and mediastinal lymph nodes was also observed. The fungus ball-like shadow was fixed on the anterior wall of the cavity and its position was not altered with the patient's movements. These radiographic findings led to suspicion that the lesion might be malignant. Transbronchial lung biopsy of the cavity wall and CT guided needle aspiration biopsy of the fungus ball-like lesion were performed. Microscopic examination revealed a squamous-cell carcinoma in both the cavity wall and the fungus ball-like lesion. There was no evidence of fungal elements. In conclusion, the meniscus sign is most often associated with benign diseases such as aspergilloma, however, one should remember that carcinoma may be a cause.
一名66岁男性,因咳嗽和咯血就诊,胸部X线和CT扫描显示右下肺野有一个伴有新月征的空洞性病变。他每天吸烟40支,约46年。最初,他被诊断为曲菌球,并接受了抗真菌药物治疗。2个月后,空洞性病变的内缘出现轻微不规则。与之前的胸部X线片相比,洞壁不规则增厚,并被浸润性密度影包围。还观察到右肺门和纵隔淋巴结肿大。真菌球样阴影固定在空洞的前壁,其位置不随患者体位变动而改变。这些影像学表现提示病变可能为恶性。对空洞壁进行了经支气管肺活检,并对真菌球样病变进行了CT引导下针吸活检。显微镜检查显示空洞壁和真菌球样病变均为鳞状细胞癌。未发现真菌成分。总之,新月征最常与曲菌球等良性疾病相关,但应记住,癌症也可能是其病因。