Takebayashi S, Hosaka M, Kubota Y, Noguchi K, Fukuda M, Ishibashi Y, Tomoda T, Matsubara S
Department of Radiology, Yokohama City University Hospital, Japan.
J Urol. 2000 Jan;163(1):42-6.
Helical computerized tomography (CT) image acquisition has led to the availability of improved data sets for CT endoscopic imaging that represent virtual endoscopy using CT. We assessed the usefulness of CT ureteroscopic imaging for diagnosing ureteral tumors.
A total of 16 patients with ureteral stenosis underwent surface rendering CT ureteroscopy after the intravenous administration of contrast material and furosemide. To distinguish ureteral tumors from ureteral strictures 2 observers blinded to other patient history and evaluation data independently and prospectively evaluated CT ureteroscopy with reformatted CT ureterograms in these 16 patients. CT ureteroscopic images were then correlated with surgical and pathological findings, which served as the gold standard.
Surgical and pathological findings in the 16 patients revealed 16 ureteral tumors, including carcinoma in 10 (carcinoma in situ in 1, fibroepithelial polyps in 2 and hyperplastic polypoids in 4), inflammatory intrinsic stricture in 2 and extrinsic stricture in 4 caused by retroperitoneal fibrosis in 2 and lymph node metastasis in 2. CT ureteroscopy correctly detected all lesions except 1 carcinoma in situ, 1 polypoid carcinoma and 1 hyperplastic polypoid. The sensitivity and specificity of CT ureteroscopy for detecting ureteral tumors and carcinoma were 81% and 100%, and 80% and 75%, respectively, when tumors without stalks were considered carcinoma.
CT ureteroscopy is useful for visualizing the complex morphology of ureteral tumors and distinguishing tumor from ureteral stricture.
螺旋计算机断层扫描(CT)图像采集为CT内镜成像提供了更好的数据集,可用于虚拟CT内镜检查。我们评估了CT输尿管镜成像在诊断输尿管肿瘤方面的实用性。
16例输尿管狭窄患者在静脉注射造影剂和呋塞米后接受了表面重建CT输尿管镜检查。为了区分输尿管肿瘤和输尿管狭窄,2名对其他患者病史和评估数据不知情的观察者独立且前瞻性地评估了这16例患者经重新格式化的CT输尿管造影的CT输尿管镜检查结果。然后将CT输尿管镜图像与作为金标准的手术和病理结果进行对比。
16例患者的手术和病理结果显示有16个输尿管肿瘤,其中10例为癌(1例原位癌、2例纤维上皮息肉、4例增生性息肉样病变),2例为炎性固有狭窄,4例为外在狭窄,其中2例由腹膜后纤维化引起,2例由淋巴结转移引起。CT输尿管镜检查正确检测出了除1例原位癌、1例息肉样癌和1例增生性息肉样病变外的所有病变。当无蒂肿瘤被视为癌时,CT输尿管镜检查检测输尿管肿瘤和癌的敏感性和特异性分别为81%和100%,以及80%和75%。
CT输尿管镜检查有助于观察输尿管肿瘤的复杂形态,并区分肿瘤与输尿管狭窄。