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伦敦注射吸毒者的自我报告过量用药情况:问题的程度与性质

Self-reported overdose among injecting drug users in London: extent and nature of the problem.

作者信息

Powis B, Strang J, Griffiths P, Taylor C, Williamson S, Fountain J, Gossop M

机构信息

National Addiction Centre, London, UK.

出版信息

Addiction. 1999 Apr;94(4):471-8. doi: 10.1046/j.1360-0443.1999.9444712.x.

Abstract

AIMS

To estimate the extent and nature of overdose and factors associated with overdose among injecting drug users in London.

DESIGN

Three hundred and twelve current injecting drug users were recruited and interviewed in community settings by a team of "privileged access interviewers".

MEASUREMENTS

A structured questionnaire was used that covered the following areas: demographic characteristics, drug use, injecting behaviour, sharing practices, severity of drug dependence, experience of overdose, injecting-related health problems and treatment history.

FINDINGS

The results showed that experience of overdose was common (38%). A majority (54%) had witnessed someone else overdose. Overdosing was not a solitary experience; over 80% of subjects who had overdosed had done so in the presence of someone else, but only 27% reported ambulances having been called. Factors found to be associated with overdose were: age at which injecting began; gender (women being more likely to experience overdose); use of alcohol; and polydrug injection. The overall rate of overdosing was one per 6 years of injecting; however, once an individual had an overdose the chance of having another increased. The risk of experiencing a first overdose fell with years of injecting.

CONCLUSIONS

Harm-reduction interventions with drug injectors should educate users on the risk factors associated with overdose and actions that should be taken when someone has overdosed. Interventions designed to reduce the risk of overdose may be more effective if they are differentially targeted on drug injectors who have already experienced an overdose.

摘要

目的

评估伦敦注射吸毒者过量用药的程度、性质以及与过量用药相关的因素。

设计

由一组“特许访问访谈员”在社区环境中招募并访谈了312名当前的注射吸毒者。

测量

使用了一份结构化问卷,涵盖以下领域:人口统计学特征、药物使用、注射行为、共用做法、药物依赖的严重程度、过量用药经历、与注射相关的健康问题以及治疗史。

结果

结果显示过量用药经历很常见(38%)。大多数人(54%)目睹过他人过量用药。过量用药并非是孤立发生的经历;超过80%的过量用药者是在他人在场的情况下发生的,但只有27%的人报告曾呼叫过救护车。发现与过量用药相关的因素有:开始注射的年龄;性别(女性更易发生过量用药);饮酒;以及多种药物注射。总体过量用药率为每注射6年发生一次;然而,一旦个体发生过一次过量用药,再次发生的几率就会增加。首次过量用药的风险会随着注射年限的增加而降低。

结论

针对吸毒注射者的减少伤害干预措施应教育使用者了解与过量用药相关的风险因素以及有人过量用药时应采取的行动。如果针对已经有过过量用药经历的吸毒注射者进行有针对性的干预,旨在降低过量用药风险的干预措施可能会更有效。

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