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[细菌稳定期生物学导论:应激的一般反应机制]

[Introduction to the biology of the bacterial stationary phase: mechanism of general response to stress].

作者信息

Golovlev E L

机构信息

Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow, Russia.

出版信息

Mikrobiologiia. 1999 Sep-Oct;68(5):623-31.

Abstract

This review is devoted to the biology of stationary-phase bacteria, occurring in a specific physiological state at which they arrive in the process of complex response to various kinds of stresses accompanying the retardation and cessation of growth and reproduction. A general account of the problem is presented. Special emphasis is placed on one of the metabolic mechanisms involved in the formation of the physiological state of stationary-phase bacteria and performing primarily protective functions (the so-called general response of cells to stresses). The relationship between this and other regulatory mechanisms involved in the transition of bacteria to the stationary phase and the maintenance of this phase is discussed.

摘要

本综述致力于研究静止期细菌的生物学特性,这些细菌处于特定的生理状态,它们是在对伴随生长和繁殖的迟缓与停止的各种应激作出复杂反应的过程中进入该状态的。文中给出了该问题的总体描述。特别强调了参与静止期细菌生理状态形成并主要发挥保护功能的一种代谢机制(即所谓的细胞对应激的一般反应)。还讨论了这一机制与细菌进入静止期及维持该阶段所涉及的其他调节机制之间的关系。

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