Kim J W, Kim S H, Cha J K
Department of Neurology, Dong-A University Hospital, Pusan.
J Neurol. 1999 Nov;246(11):1075-9. doi: 10.1007/s004150050515.
Thalamic lesions give rise to a variety of clinical syndromes including choreoathetotic movements and ataxic hemiparesis as well as sensory deficits. We describe four patients exhibiting pseudochoreoathetosis, hypesthesia, and ataxic hemiparesis in the limbs contralateral to a thalamic lesion. Three of the four patients showed the involuntary movements within 10 days of stroke onset; the remaining patient was not seen until 4 years later. Three had infarction and the other one hemorrhage in the posterior and lateral thalamus. All the patients had both cerebellar and sensory ataxia. These cases suggest that failure to convey proprioceptive information be the basic pathophysiology of pseudochoreoathetosis.
丘脑病变会引发多种临床综合征,包括舞蹈手足徐动症、共济失调性偏瘫以及感觉障碍。我们描述了4例患者,他们在丘脑病变对侧的肢体出现假性舞蹈手足徐动症、感觉减退和共济失调性偏瘫。4例患者中有3例在卒中发作后10天内出现了不自主运动;其余1例患者在4年后才被发现。3例为丘脑后部和外侧梗死,另1例为出血。所有患者均有小脑性和感觉性共济失调。这些病例表明,无法传递本体感觉信息是假性舞蹈手足徐动症的基本病理生理学机制。