Hart W, van Gijn J
Ned Tijdschr Geneeskd. 1999 Dec 18;143(51):2553-6.
Two patients are described who were originally published in Reports of medical cases (1827; 1831) by Richard Bright. The first patient suffered from haematuria and oedema (dropsy) and died after acute epiglottitis. At autopsy the kidneys were swollen and haemorrhagic (acute glomerulonephritis in present terms). The second patient died after two episodes of acute headache and decreased consciousness. At autopsy an aneurysmatic dilatation of a brain artery was found. Today the diagnosis of acute glomerulonephritis or subarachnoid haemorrhage would have been made from the history and physical examination, and newly developed laboratory and histological techniques would have been helpful in securing it. But even nowadays, clinical skills are still continually expanding by feedback from new diagnostic techniques.
本文描述了两名患者,他们最初由理查德·布莱特发表于《医学病例报告》(1827年;1831年)。第一名患者患有血尿和水肿(积水),并在急性会厌炎后死亡。尸检时发现肾脏肿大且出血(按现在的说法是急性肾小球肾炎)。第二名患者在两次急性头痛和意识减退发作后死亡。尸检时发现一条脑动脉有动脉瘤样扩张。如今,根据病史和体格检查就可以做出急性肾小球肾炎或蛛网膜下腔出血的诊断,新开发的实验室和组织学技术也有助于确诊。但即使在如今,临床技能仍在通过新诊断技术的反馈不断扩展。