前部模式的起源。我们的头部是何时形成的？

Origin of anterior patterning. How old is our head?

作者信息

Galliot B, Miller D

机构信息

Department of Zoology and Animal Biology, University of Geneva, Switzerland.

出版信息

Trends Genet. 2000 Jan;16(1):1-5. doi: 10.1016/s0168-9525(99)01888-0.

DOI:10.1016/s0168-9525(99)01888-0

PMID:10637621

Abstract

Most animals that display a bilateral symmetry (bilaterians) share homologous regulatory genes involved in head development. Recently, homologues of several of these genes have been cloned from animals that are radially organized, such as coral, sea anemones, jellyfish or hydra (cnidarians). Surprisingly, some of these are expressed apically and/or during apical patterning in hydrozoans, suggesting that head patterning is much older than previously thought.

摘要

大多数呈现两侧对称的动物（两侧对称动物）共享参与头部发育的同源调控基因。最近，其中一些基因的同源物已从呈辐射状组织的动物中克隆出来，如珊瑚、海葵、水母或水螅（刺胞动物）。令人惊讶的是，其中一些基因在水螅虫纲动物的顶端和/或顶端模式形成过程中表达，这表明头部模式形成比之前认为的要古老得多。