Ramírez-Segura R, Campos-Castelló J, González-Mateos M J, López-Lafuente A, Reina-Durán M T, de Santos M T, Careaga-Maldonado J
Servicio de Neuropediatría, Hospital Clínico San Carlos, Madrid, España.
Rev Neurol. 1999;29(11):1017-9.
To determine whether visual evoked potentials (VEP) change, and to what degree, in different types of headache (migraine with or without aura, or tension headache).
We made a transversal study of 78 children (aged 3-14 years) studied between March 1997 and August 1998, classified into three groups according to HIS diagnostic criteria of 1988 and HIS-R 1997. A VEP of geometric pattern was done using the recording technique recommended by the International Society in their standards for VEP and the reference values were used for an amplitude of less than 5 microV and a latency of P100 +/- 15 ms. The qualitative variable was frequency, and the quantitative variables were the mean and the standard deviation. We studied the association between qualitative variables using the chi-squared test and the differences in means between the groups with ANOVA. All differences were considered to be statistically significant when p < 0.05.
Girls made up 55%, with an average age of 8.84 years and a standard deviation of 3 years. There were no statistically significant differences in the mean of the VEP findings between the different types of headache with regard to amplitude (p = 0.975) and latency (p = 0.941). Neither were there any significant differences in the response to VEP in the different types of headache as far as sex and age were concerned, with p = 0.268 and p = 0.147 respectively.
Our results show no statistically significant differences and do not support the idea of using VEP as a neurophysiological method for studying headaches and differentiating the various types.
确定不同类型头痛(有或无先兆偏头痛、紧张性头痛)时视觉诱发电位(VEP)是否改变以及改变程度。
我们对1997年3月至1998年8月间研究的78名儿童(3 - 14岁)进行了横向研究,根据1988年HIS诊断标准和1997年HIS - R将其分为三组。使用国际社会在VEP标准中推荐的记录技术进行几何图形VEP检查,参考值为振幅小于5微伏、P100潜伏期为±15毫秒。定性变量为频率,定量变量为均值和标准差。我们使用卡方检验研究定性变量之间的关联,使用方差分析研究组间均值差异。当p < 0.05时,所有差异均被认为具有统计学意义。
女孩占55%,平均年龄8.84岁,标准差3岁。不同类型头痛在VEP结果的均值方面,振幅(p = 0.975)和潜伏期(p = 0.941)均无统计学显著差异。就性别和年龄而言,不同类型头痛对VEP的反应也无显著差异,p值分别为0.268和0.147。
我们的结果显示无统计学显著差异,不支持将VEP作为研究头痛及区分不同类型头痛的神经生理学方法这一观点。