Nebreda C L, Urban B J, Taylor A E
Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Reg Anesth Pain Med. 2000 Jan-Feb;25(1):69-71. doi: 10.1016/s1098-7339(00)80014-0.
Long-standing limb pain typically has a multifactorial etiology not amenable to causal therapy. We present a case of chronic progressing upper extremity pain caused by a glomus tumor; the excision was curative.
A 39-year-old woman presented with 10-year history of constant deep internal throbbing, aching pain localized to the radial aspect of the left index finger and additional intermittent shooting pains radiating up the arm toward the shoulder. Pain was increased after minor local trauma, following cold exposure, and for unknown reasons. A blotchy, bluish skin discoloration could appear on the radial aspect of the index finger during severe pain. Nonsteroidal antinflammatory drugs, narcotics, amitriptyline, local heat, bracing, and a sympathetic nerve block had all been ineffective. The physical examination was characterized by exquisite pressure tenderness over the radial aspect of the left index finger, most pronounced just distal to the distal interphalengeal joint.
Inflation of a left arm blood pressure cuff to above systolic pressures abolished pain. A glomus tumor was suspected and confirmed by histologic examination.
Glomus tumors are rare, benign neoplasms (1 to 5% of all hand tumors), developing from neuromyoarterial glomus bodies. They usually present with pain and may mimic other painful conditions, delaying the average time until diagnosis for up to 10 years. The classic diagnostic triad consists of local pain, pressure tenderness, and cold hypersensitivity. Abolition of pain following inflation of a blood pressure cuff to above systolic levels (ischemia test) is highly diagnostic. We suggest routine use of this test in cases of upper limb pain of unclear etiology.
长期肢体疼痛通常病因多因素,难以进行病因治疗。我们报告一例由血管球瘤引起的慢性进行性上肢疼痛病例,手术切除后治愈。
一名39岁女性,有10年持续深部搏动性、酸痛病史,疼痛局限于左手食指桡侧,另有间歇性刺痛沿手臂向上放射至肩部。轻微局部创伤、暴露于寒冷环境后及不明原因时疼痛会加重。严重疼痛时,食指桡侧可出现斑片状、 bluish皮肤变色。非甾体抗炎药、麻醉药、阿米替林、局部热敷、支具固定及交感神经阻滞均无效。体格检查的特点是左手食指桡侧有明显的压痛,在远侧指间关节远侧最为明显。
将左臂血压袖带充气至收缩压以上可缓解疼痛。怀疑为血管球瘤,并经组织学检查证实。
血管球瘤是罕见的良性肿瘤(占所有手部肿瘤的1%至5%),由神经肌动脉血管球体制成。它们通常表现为疼痛,可能模仿其他疼痛性疾病,将平均诊断时间延迟长达10年。典型的诊断三联征包括局部疼痛、压痛和冷过敏。将血压袖带充气至收缩压以上水平后疼痛缓解(缺血试验)具有高度诊断价值。我们建议在病因不明的上肢疼痛病例中常规使用此试验。