Jankowska A, Veillette Y
Department of Anesthesia, Centre Hospitalier de Gatineau, Montréal, Québec.
Can J Anaesth. 2000 Feb;47(2):137-42. doi: 10.1007/BF03018849.
To compare the extent of the sensory, motor and sympathetic block produced by a single dose of 60 mg lidocaine at the same concentration (2%) and volume but at different baricity injected intraspinally.
In a randomised double blind study, 40 ASA I-II patients were scheduled for elective surgery (orthopedic, urologic, peripheral vascular and lower digestive procedure). They were divided in two groups. Twenty patients received 60 mg lidocaine 2% in a hyperbaric solution and 20 received 60 mg lidocaine 2% in a isobaric solution. The levels of sensory (pinprick, ice) motor (Bromage scale) and sympathetic blockade (galvanometry, cutaneous blood flow, temperature) were measured at 0, 5, 10, 15, 20 and 30 min.
There were no differences between the groups with regard to maximal height of sympathetic block, sensory level to pinprick: T5 +/-2.4 for isobaric group, T6 +/-3.6 for hyperbaric group or to cold: T3 +/-2.3 for isobaric group, T4 +/-2.7 for hyperbaric group. Hyperbaric lidocaine 2% produced a more pronounced sensory (pinprick, ice) and motor block on the dependant than on the non-dependant side.
The baricity of 60 mg lidocaine injected intraspinally in the lateral decubitus position did not influence the cephalad spread of sensory or sympathethic blockade. In the hyperbaric group, the dependent side showed a more pronounced sensory (pinprick, ice), and motor block.
比较经脊髓注射相同浓度(2%)、相同体积但不同比重的60毫克利多卡因单次给药所产生的感觉、运动和交感神经阻滞程度。
在一项随机双盲研究中,40例美国麻醉医师协会(ASA)分级为I-II级的患者计划接受择期手术(骨科、泌尿科、外周血管和下消化道手术)。他们被分为两组。20例患者接受2%高比重溶液中的60毫克利多卡因,20例患者接受2%等比重溶液中的60毫克利多卡因。在0、5、10、15、20和30分钟时测量感觉(针刺、冰敷)、运动(布罗麻量表)和交感神经阻滞(电流测定、皮肤血流、温度)水平。
两组在交感神经阻滞的最大高度、针刺感觉平面(等比重组为T5±2.4,高比重组为T6±3.6)或冷觉感觉平面(等比重组为T3±2.3,高比重组为T4±2.7)方面没有差异。2%高比重利多卡因在受压侧产生的感觉(针刺、冰敷)和运动阻滞比非受压侧更明显。
在侧卧位经脊髓注射60毫克利多卡因的比重不影响感觉或交感神经阻滞的头端扩散。在高比重组中,受压侧显示出更明显的感觉(针刺、冰敷)和运动阻滞。