[伴放线放线杆菌的血清型分布]

[Serotype distribution of Actinobacillus actinomycetemcomitans].

作者信息

Wang Z, Yang S, Shang J

机构信息

Beijing Hospital for Stomatology, Capital Medical University.

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 1997 Jan;32(1):7-9.

PMID:10677934

Abstract

A total of 131 Actinobacillus actinomycetemcomitans clinical strains from 28 periodontally healthy or diseased subjects were serologically categorized by indirect enzyme-linked immnosorbent assay. Sepecies-specific and serotype b, c-specific monoclonal antibodies against Actinobacillus actinomycetemcomitans were used. Preliminary data revealed that each subject harbored only one serotype of Actinobacillus actinomycetemcomitans. The distribution of serotype a, b and c were respectively 11%, 21% and 68%, both of periodontally healthy subjects harbered serotype b, 7 of 9 juvenile periodontitis subjects harbered serotype c, 12 of the other subjects which included 3 adult periodontitis and 14 gingivitis harbered serotype c.

摘要

通过间接酶联免疫吸附测定法，对来自28名牙周健康或患病受试者的总共131株伴放线放线杆菌临床菌株进行了血清学分类。使用了针对伴放线放线杆菌的种特异性以及血清型b、c特异性单克隆抗体。初步数据显示，每个受试者仅携带一种伴放线放线杆菌血清型。血清型a、b和c的分布分别为11%、21%和68%，牙周健康受试者均携带血清型b，9名青少年牙周炎受试者中有7名携带血清型c，其他受试者（包括3名成人牙周炎患者和14名牙龈炎患者）中有12名携带血清型c。