High-frequency dielectric study of side-chain dynamics in poly(lysine) aqueous solutions.

The high-frequency dielectric properties of poly(lysine) of different chirality in aqueous solutions have been measured in the frequency range from 1 MHz to 1.8 GHz. The dielectric spectra show the existence of relatively small dielectric dispersions at around 100 MHz that have been attributed to internal motion in the polymer chain, due to side-chain polar groups. Our results indicate that the local structure of the chain and its possibility to undergo a conformational transition induced by pH does not modify the main feature of the side-chain dynamics, the dielectric strength being largely proportional to the concentration of charged groups. A similar behavior has been found in poly(alpha-glutamate) and in poly(gamma-glutamate) aqueous solutions, where the dielectric parameters appear to be related to the change in the charge density on the main chain, rather than to the accompanying conformational helix-coil transition.