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Adamantylamide dipeptide stimulates hematopoiesis and increases survival in irradiated mice.

作者信息

Hofer M, Vacek A, Masek K, Juchelková L, Pipalová I

机构信息

Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, CZ-612 65, Brno, Czech Republic.

出版信息

Int J Immunopharmacol. 2000 Jan;22(1):91-7. doi: 10.1016/s0192-0561(99)00072-7.

Abstract

It has been demonstrated that the synthetic immunostimulatory compound, adamantylamide dipeptide (AdDP) produces hematopoiesis-stimulating effects in mice exposed to sublethal doses of ionizing radiation and increases survival in experimental animals irradiated with a lethal dose. These findings might suggest contingent extension of clinical indications for the administration of AdDP for the conditions of hematopoietic suppression, especially in oncology.

摘要

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