Sørensen E, Johansen M V, Schou T W, Bøgh H O
Danish Center for Experimental Parasitology, The Royal Veterinary and Agricultural University, Frederiksberg C, Denmark.
Southeast Asian J Trop Med Public Health. 1999 Mar;30(1):32-5.
The current study sought to elucidate a possible association between age and susceptibility to a primary infection with Schistosoma japonicum in pigs. Sixteen Landrace/Yorkshire crossbred specific pathogen-free pigs in three different age groups (group A-C), aged approximately 7, 24 and 37 weeks at the beginning of the experiment, were infected by intramuscular injections of 1,000, 1,500 or 2,400 cercariae, respectively. Fecal egg counts were obtained twice weekly from six to eight weeks post infection (wpi), and the pigs were killed 11 wpi. The number of worms collected were counted and sexed subsequent to perfusion. Tissue egg counts were estimated on samples from the liver. The worm recoveries for group A, B and C were 3.2%, 8.1% and 3.8%, respectively. No differences were observed between the male/female ratios of the three groups. The fecundity parameters, ie, fecal egg counts per mature female and liver egg counts per mature female, showed no significant differences between the three age groups. The results did not indicate any difference in susceptibility between the different age-groups of pigs to a primary infection with S. japonicum.
本研究旨在阐明猪的年龄与日本血吸虫初次感染易感性之间可能存在的关联。在实验开始时，将16头长白/约克夏杂交的无特定病原体猪分为三个不同年龄组（A - C组），分别约为7周龄、24周龄和37周龄，每组分别通过肌肉注射1000、1500或2400条尾蚴进行感染。在感染后6至8周期间，每周两次收集粪便虫卵计数，在感染后11周处死猪。灌注后对收集到的虫体进行计数和鉴别雌雄。对肝脏样本进行组织虫卵计数估计。A组、B组和C组的虫体回收率分别为3.2%、8.1%和3.8%。三组的雌雄比例之间未观察到差异。繁殖力参数，即每只成熟雌虫的粪便虫卵计数和每只成熟雌虫的肝脏虫卵计数，在三个年龄组之间未显示出显著差异。结果表明，不同年龄组的猪对日本血吸虫初次感染的易感性没有差异。
