Nelson K A, Walsh D, Abdullah O, McDonnell F, Homsi J, Komurcu S, LeGrand S B, Zhukovsky D S
Harry R. Horvitz Center for Palliative Medicine, the Department of Hematology/Medical Oncology, and the Taussig Cancer Center, The Cleveland Clinic, OH 44195, USA.
Semin Oncol. 2000 Feb;27(1):34-44.
Complications due to cancer and its treatment are common and increase in incidence and severity as the disease progresses. Central nervous system complications affect 15% to 20% of patients, and up to 75% have bone metastases at some point during the disease process. Endocrine abnormalities include hypercalcemia, adrenal insufficiency, and inappropriate antidiuretic syndrome. Hematologic disorders, malignant effusions, and gastrointestinal (GI) problems may cause significant morbidity.
癌症及其治疗引发的并发症很常见，且随着疾病进展，其发生率和严重程度都会增加。中枢神经系统并发症影响15%至20%的患者，高达75%的患者在疾病过程中的某个阶段会发生骨转移。内分泌异常包括高钙血症、肾上腺功能不全和抗利尿激素分泌失调综合征。血液系统疾病、恶性积液和胃肠道问题可能导致严重的发病率。
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