Yoshii F, Kozuma R, Haida M, Shinohara Y, Yoshitake M, Abe S, Handa S
Department of Neurology, Tokai University School of Medicine, Kanagawa, Japan.
Acta Neurol Scand. 2000 Mar;101(3):212-5. doi: 10.1034/j.1600-0404.2000.101003212.x.
A Guillain-Barré syndrome patient showed giant negative T waves on electrocardiography at the height of the disease, with large left ventricular hypokinesis on echocardiography and extensive defects on 123I-meta-iodobenzylguanidine myocardial scintigraphy. Gamma-globulin improved the neurological symptoms, and the above abnormalities resolved. We speculate that cardiac sympathetic nerve endings were transiently damaged, with consequent myocardial injury, due to norepinephrine toxicity.
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