一名儿童左肱三头肌的Castleman病，怀疑是儿童小圆细胞肿瘤。

Castleman's disease of the left triceps in a child suspected to be a small round cell tumor of childhood.

作者信息

Fiel-Gan M D, Voytek T M, Weiss R G, Brown R T, Joshi V V

机构信息

Department of Pathology, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102, USA.

出版信息

Pediatr Dev Pathol. 2000 May-Jun;3(3):286-9. doi: 10.1007/s100249910038.

DOI:10.1007/s100249910038

PMID:10742418

Abstract

Castleman's disease (CD) is histologically characterized by a proliferation of polyclonal small lymphocytes and plasma cells. The clinical presentation varies widely, but most commonly manifests as a solitary mediastinal mass, incidentally found on radiographic examination. We present a case of a 10-year-old girl who exhibited a left arm mass which, preoperatively and on frozen section, was diagnosed as a small round cell tumor of childhood (SRCT). This report emphasizes the unusual location of CD in the soft tissue and as a rare entity to be considered in the differential diagnosis of SRCT.

摘要

卡斯特曼病（CD）在组织学上的特征是多克隆小淋巴细胞和浆细胞增殖。临床表现差异很大，但最常见的表现是在影像学检查中偶然发现的孤立性纵隔肿块。我们报告一例10岁女孩，其左臂有一肿块，术前及冰冻切片诊断为儿童小圆细胞肿瘤（SRCT）。本报告强调了CD在软组织中的不寻常位置，以及作为SRCT鉴别诊断中需考虑的罕见实体。