Van Offel J F, De Gendt C M, De Clerck L S, Stevens W J
Department of Immunology, Allergy and Rheumatology, University Hospital of Antwerp, Belgium.
Clin Rheumatol. 2000;19(1):64-6. doi: 10.1007/s100670050014.
The clinical manifestations of hypoparathyroidism are mainly characterised by increased neuromuscular irritability as a consequence of hypocalcaemia. Occasionally, elevation of the muscle enzymes may mimic polymyositis. Reduced parathyroid hormone production, but also vitamin D treatment and calcium supplementation, may contribute to the increased bone mass found in patients with postsurgical hypoparathyroidism. We report the case of a 36-year-old woman with untreated idiopathic hypoparathyroidism and a high bone mass despite severe muscle impairment due to hypocalcaemic myopathy.
甲状旁腺功能减退的临床表现主要特征为因低钙血症导致神经肌肉兴奋性增加。偶尔,肌肉酶升高可能类似多发性肌炎。甲状旁腺激素分泌减少,以及维生素D治疗和补钙,可能导致术后甲状旁腺功能减退患者骨量增加。我们报告了一例36岁女性,患有未经治疗的特发性甲状旁腺功能减退,尽管因低钙性肌病导致严重肌肉损伤,但骨量却很高。