Delis K T, Azizi Z A, Stevens R J, Wolfe J H, Nicolaides A N
Irvine Laboratory for Cardiovascular Investigation and Research Academic Vascular Surgery, Imperial College School of Medicine, London, UK.
Eur J Vasc Endovasc Surg. 2000 Mar;19(3):261-9. doi: 10.1053/ejvs.1999.1047.
intermittent pneumatic compression (IPC) of the foot (IPC(foot)), calf (IPC(calf)) or both (IPC(foot+calf)) augments calf inflow, and improves the walking ability and peripheral haemodynamics of claudicants (IPC(foot), IPC(foot+calf)), largely due to venous outflow enhancement. This cohort study, using direct pressure measurements in healthy limbs, determines the optimal combination of frequency (2-4 impulses/minute), applied pressure (60-140 mmHg), mode (IPC(foot)-IPC(calf)-IPC(foot+calf)) and delay time of calf-to-foot impulse (0 s-0.5 s-1 s) that enables IPC to generate an almost complete and sustained decrease in venous pressure.
(a) IPC(foot)at 120 and 80 mmHg generated lower venous pressure than that with 100 and 60 mmHg (p=0.036) respectively, for 2-4 impulses/minute; venous pressure differences between applied pressures of 140 and 120 mmHg or between 80 and 100 mmHg were insignificant. (b) Venous pressure with IPC(calf)at 80 mmHg was lower than that with 60 mmHg (p=0.036) (2-4 cycles/minute); differences in venous pressure between applied pressures of 140 and 100 mmHg or between 120 and 80 mmHg were insignificant. (c) At applied pressures 60-140 mmHg, IPC(foot+calf)with one-second delay generated lower venous pressure than that with half-second delay (p=0.036), the latter being more efficient than zero delay; increasing applied pressures produced lower venous pressure, but differences were small. Venous pressure decreased with increasing IPC frequency (from 2 to 3-4/minute), at applied pressures 60-140 mmHg.
IPC(foot+calf)at applied 120-140 mmHg, a frequency of 3-4 impulses/minute and one-second delay, provided the optimum intermittent pneumatic stimulus.
对足部（IPC(足部)）、小腿（IPC(小腿)）或两者（IPC(足部 + 小腿)）进行间歇性气动压迫可增加小腿血流量，并改善跛行者的行走能力和外周血流动力学（IPC(足部)、IPC(足部 + 小腿)），这主要归因于静脉流出量的增加。本队列研究通过对健康肢体进行直接压力测量，确定频率（2 - 4次/分钟）、施加压力（60 - 140 mmHg）、模式（IPC(足部)-IPC(小腿)-IPC(足部 + 小腿)）以及小腿到足部脉冲的延迟时间（0秒 - 0.5秒 - 1秒）的最佳组合，以使IPC能够使静脉压力几乎完全且持续下降。
(a) 对于2 - 4次/分钟的频率，IPC(足部)在120 mmHg和80 mmHg时产生的静脉压力分别低于100 mmHg和60 mmHg时产生的静脉压力（p = 0.036）；140 mmHg与120 mmHg或80 mmHg与100 mmHg的施加压力之间的静脉压力差异不显著。(b) IPC(小腿)在80 mmHg时的静脉压力低于60 mmHg时的静脉压力（p = 0.036）（2 - 4次/分钟）；140 mmHg与100 mmHg或120 mmHg与80 mmHg的施加压力之间的静脉压力差异不显著。(c) 在60 - 140 mmHg的施加压力下，延迟1秒的IPC(足部 + 小腿)产生的静脉压力低于延迟0.5秒时产生的静脉压力（p = 0.036），延迟0.5秒比延迟0秒更有效；增加施加压力会使静脉压力降低，但差异较小。在60 - 140 mmHg的施加压力下，静脉压力随着IPC频率的增加（从2次/分钟增加到3 - 4次/分钟）而降低。
施加120 - 140 mmHg压力、频率为3 - 4次/分钟且延迟1秒的IPC(足部 + 小腿)提供了最佳的间歇性气动刺激。
