处于绝经过渡阶段的女性的激素生殖状态与一组生殖年龄中期女性的激素生殖状态的比较。
Hormonal reproductive status of women at menopausal transition compared to that observed in a group of midreproductive-aged women.
作者信息
Sengos C, Iatrakis G, Andreakos C, Xygakis A, Papapetrou P
机构信息
Dept. of Obstet.-Gynecol., Alexandra Gen. Hospital, Athens, Greece.
出版信息
Clin Exp Obstet Gynecol. 2000;27(1):54-6.
OBJECTIVE
To compare the serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), estradiol (E2), testosterone (T) and dehydroepiandrosterone sulfate (DHEA-S) in perimenopausal women to the levels of the same reproductive hormones in younger women.
METHODS
This was a case control study which compared the hormonal status (circulating levels of FSH, LH, PRL, T, E2, DHEA-S) between women at menopausal transition and younger mid-reproductive-aged controls. The t-test for independent samples was used.
RESULTS
FSH, LH and E2 were higher, and T and DHEA-S were lower in perimenopausal women.
CONCLUSION
The reproductive hormonal patterns in perimenopausal women favor a relatively hypergonadotropic hyper-estrogenic milieu.
目的
比较围绝经期女性血清中卵泡刺激素（FSH）、黄体生成素（LH）、催乳素（PRL）、雌二醇（E2）、睾酮（T）和硫酸脱氢表雄酮（DHEA-S）的水平与年轻女性相同生殖激素的水平。
方法
这是一项病例对照研究，比较了处于绝经过渡期的女性与年轻的生殖中期对照女性之间的激素状态（FSH、LH、PRL、T、E2、DHEA-S的循环水平）。使用独立样本t检验。
结果
围绝经期女性的FSH、LH和E2较高，而T和DHEA-S较低。
结论
围绝经期女性的生殖激素模式有利于相对高促性腺激素性高雌激素环境。
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