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代谢途径的定量、可扩展离散事件模拟

Quantitative, scalable discrete-event simulation of metabolic pathways.

作者信息

Meric P A, Wise M J

机构信息

Basser Department of Computer Science, University of Sydney, Australia.

出版信息

Proc Int Conf Intell Syst Mol Biol. 1999:187-94.

Abstract

DMSS (Discrete Metabolic Simulation System) is a framework for modelling and simulating metabolic pathways. Quantitative simulation of metabolic pathways is achieved using discrete-event techniques. The approach differs from most quantitative simulators of metabolism which employ either time-differentiated functions or mathematical modelling techniques. Instead, models are constructed from biochemical data and biological knowledge, with accessibility and relevance to biologists serving as key features of the system.

摘要

离散代谢模拟系统(DMSS)是一个用于代谢途径建模和模拟的框架。代谢途径的定量模拟是使用离散事件技术实现的。该方法不同于大多数代谢定量模拟器,后者采用时间微分函数或数学建模技术。相反,模型是根据生化数据和生物学知识构建的,系统的关键特性是便于生物学家使用且与他们相关。

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