Cepeda M L, Allen F H, Cepeda N J, Yang Y M
Department of Psychiatry, University of South Alabama, Mobile 36617-2293, USA.
J Natl Med Assoc. 2000 Jan;92(1):10-4.
This study assessed delays in physical growth and sexual maturation, self-esteem and body image in youth with homozygous sickle hemoglobin disease (HgbSS).
A consecutive sample of 30 subjects age 8 through 19 with homozygous sickle cell disease (hemoglobin SS) and a similar number of control subjects matched for age, race, gender and socioeconomic status and free of chronic illness were examined for height, weight and Tanner staging of sexual development. Subjects also completed the Body Cathexis Scale and Piers-Harris Self-Concept Scale. Assessments were with paired samples t-tests.
The subjects with sickle cell disease had significantly lower weights and were shorter than matched control subjects. Sexual development (physical) was also delayed in the sickle cell subjects. The study failed to find significant differences for either body image or self-esteem.
The latency age and adolescent subjects with sickle cell disease had significant delays in physical (height, weight, secondary sexual characteristics) maturation. The study failed to find significant differences in either self-esteem or body image between the two groups. Theoretical constructs from the literature were presented which questioned the belief that these expected delays in physical growth and sexual maturation have an adverse effect upon self-esteem and body image.
本研究评估了纯合子镰状血红蛋白病（HgbSS）青少年的身体生长和性成熟延迟情况、自尊及身体意象。
对30名年龄在8至19岁的纯合子镰状细胞病（血红蛋白SS）患者进行连续抽样，并选取了数量相近、年龄、种族、性别和社会经济地位相匹配且无慢性病的对照对象，对其身高、体重及性发育的坦纳分期进行检查。研究对象还完成了身体投入量表和皮尔斯 - 哈里斯自我概念量表。评估采用配对样本t检验。
镰状细胞病患者的体重显著低于匹配的对照对象，身高也更矮。镰状细胞病患者的性发育（身体方面）也延迟。该研究未发现身体意象或自尊方面存在显著差异。
镰状细胞病的潜伏期年龄和青少年患者在身体（身高、体重、第二性征）成熟方面存在显著延迟。该研究未发现两组之间在自尊或身体意象方面存在显著差异。文中呈现了文献中的理论架构，这些架构对身体生长和性成熟的预期延迟会对自尊和身体意象产生不利影响这一观点提出了质疑。
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