Hagemann D, Bauer K H, Kemen M, Schmidt W E, Adamek R J
Medizinische Klinik I, St. Josef-Hospital, Ruhr-Universität Bochum.
Dtsch Med Wochenschr. 2000 Apr 14;125(15):455-8. doi: 10.1055/s-2007-1024262.
A 55-year-old woman had for 5 years been suffering from severe burning thoracic pain. She had typical risk factors for cardiovascular disease, namely hypertension, chronic smoking, obesity and hypercholesterolaemia. She had been hospitalized several times for suspected myocardial infarction, but coronary heart disease had been excluded by cardiac examination, including angiocardiography. The only contributory admission finding was epigastric pain on pressure.
Gastroscopy revealed a non-erosive duodenitis and chronic antral gastritis. The cardia was tightly closed and there were no signs of reflux oesophagitis. Manometry in the oesophagus showed frequent simultaneous contractions and marked increase in pressure amplitude, predominantly in the distal segment, indicating diffuse oesophageal spasms.
Drug treatment with calcium channel blockers gave only brief relief from the thoracic pain. But longitudinal oesophageal myotomy via thoracoscopy brought about complete pain relief, which has now persisted for 3 years.
Thoracoscopic longitudinal oesophageal myotomy can provide a therapeutic alternative in patients with oesophageal spasms when drug therapy and pneumatic oesophageal dilatation have failed.
一名55岁女性遭受严重的胸部灼痛达5年之久。她具有典型的心血管疾病风险因素,即高血压、长期吸烟、肥胖和高胆固醇血症。她曾因疑似心肌梗死多次住院,但通过包括心血管造影在内的心脏检查排除了冠心病。唯一相关的入院检查发现是上腹部压痛。
胃镜检查显示非糜烂性十二指肠炎和慢性胃窦炎。贲门紧闭,无反流性食管炎迹象。食管测压显示频繁的同步收缩且压力幅度显著增加,主要在远端节段,提示弥漫性食管痉挛。
使用钙通道阻滞剂进行药物治疗仅能短暂缓解胸痛。但通过胸腔镜进行的食管纵向肌切开术带来了完全的疼痛缓解,目前已持续3年。
当药物治疗和食管气囊扩张失败时,胸腔镜下食管纵向肌切开术可为食管痉挛患者提供一种治疗选择。