Bushra J S
Department of Emergency Medicine, Medical College of Pennsylvania Hospital, Philadelphia, Pennsylvania 19107, USA.
J Emerg Med. 2000 May;18(4):427-30. doi: 10.1016/s0736-4679(00)00158-x.
The syndrome of ophthalmoplegia, ataxia, and areflexia was first described in 1956 by Miller Fisher. This syndrome has long been believed to be a variant of Guillain-Barré syndrome (GBS), mainly because of its areflexia, cerebrospinal fluid findings, and its postinfectious presentation. The case of an 11-year-old male with Miller Fisher syndrome (MFS) is described. MFS differs from GBS in several key clinical features and presents an extensive and challenging differential diagnosis. It is useful to recognize MFS as both a variant of GBS and a distinct entity with its own therapeutic considerations.
眼肌麻痹、共济失调和无反射综合征于1956年由米勒·费希尔首次描述。长期以来,该综合征一直被认为是吉兰-巴雷综合征(GBS)的一种变异型,主要是因为其无反射、脑脊液检查结果以及感染后表现。本文描述了一名11岁男性患米勒·费希尔综合征(MFS)的病例。MFS在几个关键临床特征上与GBS不同,并且呈现出广泛且具有挑战性的鉴别诊断。将MFS既视为GBS的一种变异型,又视为具有自身治疗考量的独特疾病实体是很有用的。