Zander R
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975 Jul 4;195(4):215-30. doi: 10.1007/BF00414935.
To investigate the O2 supply conditions of the corneal endothelium and the lens by the aqueous hymor, O2 solubility coefficients of aqueous humor as well as in the lens had to be determined. The current assumption that the vitreous body is a possible O2 pool had to be examined. The following conclusions are drawn from the measured values of Bunsel O2 solubility coefficients (ml O2ml atm) of bovine aqueous humor, lens homogenates, vitreous bodys as well as of solutions of hyaluronic acid at temperatures from 10 to 40 degrees C: 1. The physiological rate of oxygen transport by the aqueous suffices to supply the corneal endothelium and the lens with oxygen, the temperature gradients within the anterior chamber favour the O2 supply of the corneal endothelium compared to other ocular tissues. 2. The O2 content of the aqueous can maintain O2 consumption of corneal endothelium for about 20 min theoretically or for about 5 min the lens ones. 3. The vitreous body can act as a possibel O2 pool only with regard to the O2 supply of the lens. In this case the pool can maintain O2 consumption of the shole lens for about 20 min. 4. During physiological growth of the lens the central part expands, which is characterized by an O2 concentration near zero. Therefore, the O2 supply of the lens is maintained for only less than one minute by the content of the lens itself.
为了通过房水研究角膜内皮和晶状体的氧气供应情况,必须测定房水以及晶状体中的氧气溶解度系数。当前关于玻璃体可能是一个氧气库的假设也必须进行检验。根据在10至40摄氏度下对牛房水、晶状体匀浆、玻璃体以及透明质酸溶液的邦塞尔氧气溶解度系数(毫升氧气/毫升·大气压)的测量值得出以下结论:1. 房水的生理氧气运输速率足以向角膜内皮和晶状体供应氧气,前房内的温度梯度相比于其他眼组织更有利于角膜内皮的氧气供应。2. 理论上,房水的氧气含量可维持角膜内皮的氧气消耗约20分钟,或晶状体的氧气消耗约5分钟。3. 仅就晶状体的氧气供应而言,玻璃体可作为一个可能的氧气库。在这种情况下,该库可维持整个晶状体的氧气消耗约20分钟。4. 在晶状体的生理性生长过程中,其中心部分会扩张,其特征是氧气浓度接近零。因此,晶状体自身的含量仅能维持晶状体一分钟不到的氧气供应。