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青年成人大型听神经瘤的经迷路切除术

Translabyrinthine removal of large acoustic neuromas in young adults.

作者信息

Wu H, Sterkers J

机构信息

Professeur Honoraire au Collège de Médecine, Hôpitaux de Paris, 4 rue Michel-Ange, 75016, Paris, France.

出版信息

Auris Nasus Larynx. 2000 Jul;27(3):201-5. doi: 10.1016/s0385-8146(00)00057-2.

Abstract

OBJECTIVE

the authors reviewed the clinical manifestations and the surgical outcomes in a series of young patients who underwent removal of large acoustic neuromas via the translabyrinthine approach.

METHODS

40 young adults who underwent a translabyrinthine removal of acoustic neuromas 3 cm or greater in size were analyzed. The patient's age ranged from 17 to 30 years. The mean size of tumor was 4.25 cm.

RESULTS

the primary symptoms are similar to those in adult but usually less intense. The average interval time between the primary symptom and the diagnosis was 17 months. A high percentage of preoperative normal hearing (35%) and good facial function (100%) were noted. Translabyrinthine approach was used in all cases. Total removal was realised in 39 patients (97.5%). The facial nerve was anatomically preserved in 37 patients (92.5%). Twenty-six patients (65%) had a good facial function (House-Brackmann grade I or II) immediately or at 1 month after surgery, 11 patients (28%) achieved grade III or IV. Three patients underwent an immediate nerve repair after tumor removal. All of them recovered to grade III or IV 1 year after surgery. Postoperative complications were minimal.

CONCLUSIONS

young adults may have a rapid growth rate but usually have minimal symptoms even with a large acoustic neuroma. The translabyrinthine approach has been used successfully in removal of large acoustic tumors of young patients, with the good result of facial nerve preservation and long-term tumor control.

摘要

目的

作者回顾了一系列经迷路后入路切除大型听神经瘤的年轻患者的临床表现和手术结果。

方法

分析了40例接受迷路后入路切除大小在3厘米及以上听神经瘤的年轻成年人。患者年龄在17至30岁之间。肿瘤平均大小为4.25厘米。

结果

主要症状与成年人相似,但通常较轻。主要症状出现至诊断的平均间隔时间为17个月。术前听力正常(35%)和面部功能良好(100%)的比例较高。所有病例均采用迷路后入路。39例患者(97.5%)实现了肿瘤全切。37例患者(92.5%)面神经得以解剖保留。26例患者(65%)在术后即刻或术后1个月面部功能良好(House-Brackmann分级I级或II级),11例患者(28%)达到III级或IV级。3例患者在肿瘤切除后立即进行了神经修复。术后1年,他们均恢复到III级或IV级。术后并发症极少。

结论

年轻成年人的听神经瘤生长速度可能较快,但即使肿瘤较大通常症状也较轻。迷路后入路已成功用于切除年轻患者的大型听神经瘤,面神经保留效果良好,肿瘤长期控制效果佳。

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