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[模型与实验。前庭适应]

[Models and experimentation. Vestibular adaptation].

作者信息

Ledoux A

出版信息

Acta Otorhinolaryngol Belg. 1975;29(1):92-102.

PMID:1082233
Abstract

In 1961, we have given the experimental proof that, in the frog, the excited or inhited electrical activity of the ampullar nerve produced by a copular deflection of long duration, showed a decline which was attributed to an "adaptation" of peripheral origin. We suggested that the "inverse phase" was due to this adaptation. Since then, many workers have showed that such an adaptation was to be found in the induced nystagmus by prolonged angular acceleration. The mathematical models constructed to explain the vestibular function have to take in account this response decline to coincide with the evolution of the slow phase velocity of the nystagmus, during the prolonged deflexions of the cupula produced by the clinical vestibular rotatory and caloric tests.

摘要

1961年,我们给出了实验证据,在青蛙中,长时间的壶腹偏斜所产生的壶腹神经的兴奋或抑制性电活动呈现出一种下降,这被归因于外周起源的“适应”。我们认为“反相”是由于这种适应。从那时起,许多研究人员表明,在长时间角加速度诱发的眼球震颤中可以发现这种适应。为解释前庭功能而构建的数学模型必须考虑到这种反应下降,以便与临床前庭旋转和冷热试验中壶腹长时间偏斜期间眼球震颤慢相速度的变化相一致。

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