Krŭsteva M, Malinova M
Akush Ginekol (Sofiia). 2000;39(1):14-7.
A study was carried out to examine the anthropometric characteristics, neonatal morbidity and mortality in newborn infants with diabetic fetopathy.
Infant anthropometric measurements were obtained, neonatal morbidity and early neonatal mortality were determined in 15 neonates with diabetic fetopathy over 6 years.
Among the study population, 33.3% of children had macrosomia. The incidence of aspiration syndrome and meconium aspiration syndrome was 40%, transient tachypnea was 33% and the observed incidence of hyaline membrane disease was 26%. The cardiologic pathology was result of patent ductus arteriosus, myocardial hypertrophy and persistent pulmonary hypertension. The most frequent biochemical changes were transient neonatal hypoglycemia and hyperbilirubinemia. The perinatal mortality rate was 26.7%, with cases of hemorrhagic disease of newborn and the incidence of neonatal thromboembolism.
Despite the current improvements of diabetes care in pregnancy, newborn infants with diabetic fetopathy have a high level of morbidity and early neonatal mortality.
开展了一项研究,以检查患有糖尿病胎儿病的新生儿的人体测量学特征、新生儿发病率和死亡率。
对15例患有糖尿病胎儿病的新生儿进行了6年的婴儿人体测量,并确定了新生儿发病率和早期新生儿死亡率。
在研究人群中,33.3%的儿童为巨大儿。吸入综合征和胎粪吸入综合征的发生率为40%,短暂性呼吸急促为33%,观察到的透明膜病发生率为26%。心脏病理学表现为动脉导管未闭、心肌肥厚和持续性肺动脉高压。最常见的生化变化是短暂性新生儿低血糖和高胆红素血症。围产期死亡率为26.7%,包括新生儿出血性疾病病例和新生儿血栓栓塞发生率。
尽管目前孕期糖尿病护理有所改善,但患有糖尿病胎儿病的新生儿仍有较高的发病率和早期新生儿死亡率。