Hermann N V, Jensen B L, Dahl E, Bolund S, Kreiborg S
Department of Pediatric Dentistry, School of Dentistry, University of Copenhagen, Denmark.
Cleft Palate Craniofac J. 2000 May;37(3):303-17. doi: 10.1597/1545-1569_2000_037_0303_ccimol_2.3.co_2.
The objective of the study was to analyze the craniofacial morphology in infants with unilateral complete cleft lip and palate (UCCLP) in which the lip and the anterior part of the palate had been surgically closed at 2 months of age and to compare the morphology with that of a control group with unilateral incomplete cleft lip (UICL) in which the lip had also been surgically closed at 2 months of age.
The sample consisted of a total of 108 cleft children all fulfilling the entry criteria, besides diagnosis, as follows: The child was of Danish origin; the age of the child was between 650 and 750 days (approximately 22 months) at the time of examination; the child was healthy except for its single cleft malformation; the surgical procedure in each group had been performed at about 2 months of age by the same surgeon. The surgical methods used were a Tennison procedure (UICL group) and a Tennison procedure supplemented by palatovomer plasty (UCCLP group).
The method of investigation was infant cephalometry in the lateral, frontal, and axial projections. Linear, angular, and area variables describing the craniofacial morphology were calculated and supplemented by mean plots from the cephalometric projections in the two groups.
Statistical analysis based on Student's t test showed that the facial morphology in the 22-month-old UCCLP group differed significantly from that of the UICL group. The most pronounced differences were found in the maxillary complex and the mandible. The deviations observed in the UCCLP group at 22 months of age were similar to those previously observed at 2 months of age. However, several of the dysmorphic traits had become less pronounced; some had remained the same; and a few had become worse with time.
本研究的目的是分析单侧完全性唇腭裂(UCCLP)婴儿的颅面形态,这些婴儿在2个月大时进行了唇和腭前部的手术闭合,并将其形态与单侧不完全性唇裂(UICL)对照组的形态进行比较,该对照组的唇也在2个月大时进行了手术闭合。
样本共包括108名符合入选标准的腭裂儿童,除诊断外,标准如下:儿童为丹麦裔;检查时儿童年龄在650至750天之间(约22个月);除单一腭裂畸形外,儿童健康;每组的手术均由同一位外科医生在约2个月大时进行。所采用的手术方法为坦尼森手术(UICL组)和坦尼森手术加腭犁骨成形术(UCCLP组)。
研究方法为婴儿头颅侧位、正位和轴位X线测量。计算描述颅面形态的线性、角度和面积变量,并辅以两组头颅侧位片的均值图。
基于学生t检验的统计分析表明,22个月大的UCCLP组面部形态与UICL组有显著差异。最明显的差异出现在上颌复合体和下颌骨。UCCLP组在22个月大时观察到的偏差与之前在2个月大时观察到的偏差相似。然而,一些畸形特征变得不那么明显;一些保持不变;还有一些随着时间的推移变得更糟。