Unger F, Domanig E, Rastl P, Salem G
Thoraxchir Vask Chir. 1976 Feb;24(1):59-65. doi: 10.1055/s-0028-1095868.
1250 protocols of heart-lung-machines, taken between 1962-1974, underwent a variance analysis. The results show that rollerpumps with high pumpvolumes (80 ccm) are not significantly lower hemolytic than rollerpumps with a pumpvolume of 40 ccm. The hemolysis stands in direct proportion to the blood flow. Membranoxygenators effect a less traumatisation than screen- and bubbleoxygenators. Furthermore the use of fresh ACD-blood shows a lower hemolysis than hemodilution and older ACD stored blood. Type and age of the vitium have no influence on the traumatic hemolysis. The use of the orthograde perfusion is significantly better than the retrograde perfusion; the use of blood-filters is no cause for traumatic hemolysis. The above mentioned results are in accordance to literature, but the facts cannot be objectivated that easily than in invitro experiments.
对1962年至1974年间采集的1250份心肺机协议进行了方差分析。结果表明,泵流量高(80立方厘米)的滚压泵的溶血程度并不显著低于泵流量为40立方厘米的滚压泵。溶血与血流成正比。膜式氧合器造成的创伤比筛孔式和鼓泡式氧合器小。此外,使用新鲜的ACD血比血液稀释和储存时间较长的ACD血溶血程度低。缺损的类型和年龄对创伤性溶血没有影响。顺行灌注的使用明显优于逆行灌注;使用血液过滤器不会导致创伤性溶血。上述结果与文献一致,但这些事实不像体外实验那样容易客观化。