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恒河猴颞下颌关节盘半月板切除术与自体移植置换的比较研究——第一部分

A comparative study on meniscectomy and autogenous graft replacement of the Rhesus monkey temporomandibular joint articular disc--Part I.

作者信息

Tong A C, Tideman H

机构信息

Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong.

出版信息

Int J Oral Maxillofac Surg. 2000 Apr;29(2):140-5.

Abstract

The aims of this study were to compare the effects of meniscectomy and autogenous graft replacement on the functions and histology of the Rhesus monkey temporomandibular joint. Eight matured Rhesus monkeys (Macaca mulatta) were used for the first part of the study to compare firstly the results of meniscectomy without replacement and secondly, replacement of the disc with a fascia lata graft. The results showed that unilateral meniscectomy in Rhesus monkeys did not result in significant morbidity. Degenerative changes (osteoarthritis) were observed in all the experimental joints with and without replacement of the articular discs. Fascia lata did not survive after grafting and did not reliably induce re-formation of an articular disc-like structure.

摘要

本研究的目的是比较半月板切除术和自体移植物置换对恒河猴颞下颌关节功能和组织学的影响。八只成年恒河猴(猕猴)用于研究的第一部分,首先比较半月板切除不置换的结果,其次比较用阔筋膜移植置换关节盘的结果。结果表明,恒河猴单侧半月板切除术并未导致明显的发病率。在所有进行和未进行关节盘置换的实验关节中均观察到退行性改变(骨关节炎)。阔筋膜移植后未能存活,也未能可靠地诱导形成类似关节盘的结构。

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