甲氨蝶呤耐药性与L5178Y细胞对二氢蝶啶的摄取。亚叶酸的选择性保护作用。 - Suppr

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Methotrexate resistance and uptake of DDMP by L5178Y cells. Selective protection with folinic acid.

作者信息

Hill B T, Price L A, Goldie J H, Harrison S I

出版信息

Eur J Cancer (1965). 1975 Aug;11(8):545-53. doi: 10.1016/0014-2964(75)90126-7.

DOI:10.1016/0014-2964(75)90126-7

PMID:1083340

Abstract

摘要

相似文献

Methotrexate resistance and uptake of DDMP by L5178Y cells. Selective protection with folinic acid.甲氨蝶呤耐药性与L5178Y细胞对二氢蝶啶的摄取。亚叶酸的选择性保护作用。

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引用本文的文献

Establishment of Vincristine-resistant and vindesine-resistant lines of murine lymphoblasts in vitro and characterisation of their patterns of cross-resistance and drug sensitivities.小鼠淋巴母细胞长春新碱抗性和长春地辛抗性细胞系的体外建立及其交叉抗性模式和药物敏感性的表征。

Cancer Chemother Pharmacol. 1982;8(2):163-9. doi: 10.1007/BF00255477.

Phase II clinical trial of DDMP (2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine) and folinic acid (CF) in solid tumors.DDMP（2,4-二氨基-5-（3',4'-二氯苯基）-6-甲基嘧啶）与亚叶酸（CF）联合用于实体瘤的II期临床试验。

Cancer Chemother Pharmacol. 1981;6(1):81-4. doi: 10.1007/BF00253014.

Phase I clinical trial and pharmacology of 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine (metoprine) (DDMP) and folinic acid (CF).2,4-二氨基-5-（3'，4'-二氯苯基）-6-甲基嘧啶（美托普林）（DDMP）与亚叶酸（CF）的I期临床试验及药理学研究

Cancer Chemother Pharmacol. 1981;6(1):75-80. doi: 10.1007/BF00253013.

Cross resistance to esters of methotrexate in a doxorubicin-resistant subline of P388 murine leukemia.在多柔比星耐药的P388小鼠白血病亚系中对甲氨蝶呤酯的交叉耐药性。

Cancer Chemother Pharmacol. 1985;15(1):31-4. doi: 10.1007/BF00257290.

Biological and biochemical properties of new anticancer folate antagonists.新型抗癌叶酸拮抗剂的生物学和生物化学特性

Cancer Metastasis Rev. 1987;5(3):251-70. doi: 10.1007/BF00047000.

Initial clinical experience with a simultaneous combination of 2,4-diamino-5(3',4'-dichlorophenyl)-6-methylpyrimidine (DDMP) with folinic acid.

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