转移性完全性葡萄胎合并存活的共存双胎。病例报告。
Metastatic complete hydatidiform mole with a surviving coexistent twin. A case report.
作者信息
Kauffman D E, Sutkin G, Heine R P, Watt-Morse M, Price F V
机构信息
Department of Obstetrics and Gynecology, Magee-Womens Hospital, Pittsburgh, Pennsylvania 15206, USA.
出版信息
J Reprod Med. 1999 Feb;44(2):131-4.
BACKGROUND
Complete hydatidiform molar pregnancy with a coexistent live fetus is a rare clinical entity with poor fetal survival and an uncertain maternal risk.
CASE
A twin gestation consisting of a complete molar pregnancy as one twin and a normal second "twin" was identified in the second trimester. The patient was managed expectantly until 28 weeks' gestation, at which time evidence of metastatic trophoblastic disease was identified. She delivered a healthy infant by cesarean section and received postoperative single-agent chemotherapy. She was disease free six months after treatment.
CONCLUSION
Patients with documented complete molar pregnancies and coexistent live fetuses present several complex clinical issues. Though successful in some instances, expectant management should be used with caution in these patients.
背景
完全性葡萄胎妊娠合并存活胎儿是一种罕见的临床情况，胎儿存活率低，母亲风险不确定。
病例
孕中期发现双胎妊娠，其中一个胎儿为完全性葡萄胎，另一个“胎儿”正常。患者一直采取期待治疗至孕28周，此时发现有滋养细胞疾病转移的证据。她通过剖宫产分娩出一名健康婴儿，并在术后接受了单药化疗。治疗后6个月她无疾病迹象。
结论
记录在案的完全性葡萄胎妊娠合并存活胎儿的患者存在几个复杂的临床问题。尽管在某些情况下取得了成功，但对这些患者应谨慎使用期待治疗。
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