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骶神经磁刺激治疗矛盾性耻骨直肠肌综合征

Sacral magnetic stimulation in paradoxical puborectalis syndrome.

作者信息

Shafik A

机构信息

Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Egypt.

出版信息

Dig Surg. 2000;17(3):268-73. doi: 10.1159/000018846.

Abstract

BACKGROUND/PURPOSE: Our earlier studies have demonstrated that sacral magnetic stimulation (MS) in the canine model, in healthy volunteers and in constipated subjects brought about a rise in rectal pressure and a decline in rectal neck (anal canal) pressure as well as rectal evacuation. Based on these results, we studied the effect of sacral MS on defecation in patients with paradoxical puborectalis syndrome (PPS).

METHODS

Eleven subjects (8 women, 3 men; age 36-53 years) with PPS were enrolled in the study. The magnetic coil was placed on the back with its center located between L4 and L5. Stimulation parameters were set at 70% of maximum intensity, 40 Hz frequency and 2 s burst length with 2 s off. During MS, the rectal neck and gastric (intra-abdominal) pressures were measured. The procedure was performed in the empty and the full rectum using the balloon expulsion test in the latter.

RESULTS

MS of the empty and balloon-filled rectum brought about a rise in the rectal pressure (p < 0.001), decline in rectal neck pressure (p < 0. 001) and no significant change in intragastric pressure (p > 0.05). The balloon was expelled by all patients.

CONCLUSIONS

Sacral MS succeeded in expelling the water-filled rectal balloon. The method is simple, easy, noninvasive, nonradiologic and can be performed on an outpatient basis in the treatment of PPS.

摘要

背景/目的:我们早期的研究表明,在犬类模型、健康志愿者和便秘患者中,骶神经磁刺激(MS)可导致直肠压力升高、直肠颈部(肛管)压力下降以及直肠排空。基于这些结果,我们研究了骶神经磁刺激对矛盾性耻骨直肠肌综合征(PPS)患者排便的影响。

方法

11名PPS患者(8名女性,3名男性;年龄36 - 53岁)纳入本研究。将磁线圈置于背部,其中心位于L4和L5之间。刺激参数设置为最大强度的70%、频率40Hz、脉冲长度2s,间歇2s。在磁刺激过程中,测量直肠颈部和胃(腹内)压力。对于直肠充盈的情况,采用气囊排出试验,在直肠空虚和充盈状态下进行该操作。

结果

直肠空虚和充盈气囊时进行磁刺激均导致直肠压力升高(p < 0.001)、直肠颈部压力下降(p < 0.001),胃内压力无显著变化(p > 0.05)。所有患者均排出了气囊。

结论

骶神经磁刺激成功排出了直肠内的充水气囊。该方法简单、易行、无创、无辐射,可在门诊进行,用于治疗PPS。

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