Gazárek F, Pohanka J, Talas M, Fingerová H, Janousková M, Krikal Z, Hamal Z
Endocrinol Exp. 1976;10(4):283-7.
In women during the third trimester of normal pregnancy and at labour the level of oxytocin and progesterone in plasma were determined by means of radioimmunoassay and the activity of oxytocinase was measured spectrophotometrically. The plasma oxytocin levels measured from the 25th week of pregnancy showed a gradual increase with the peak values at the 39th and 40th week. At labour, the oxytocin values remain at the same level as these found at the end of pregnancy. The increase in oxytocin levels at contractions compared to its values found between contractions was not statistically significant. Oxytocinase levels showed also an ascending character until the 38th week of pregnancy. Later, a decrease was found which continued until the termination of pregnancy. At labour, there was a decrease in progesterone level in plasma which was about at the limit of significance.
在正常妊娠晚期及分娩期的女性中，采用放射免疫分析法测定血浆中催产素和孕酮的水平，并通过分光光度法测定催产素酶的活性。从妊娠第25周开始测量的血浆催产素水平呈逐渐上升趋势，在第39周和第40周达到峰值。分娩时，催产素值与妊娠末期的水平相同。与宫缩间期相比，宫缩时催产素水平的升高无统计学意义。催产素酶水平在妊娠第38周前也呈上升趋势。此后，发现其水平下降，并持续至妊娠结束。分娩时，血浆中孕酮水平下降，其下降幅度接近显著水平。
