Bonacchi M, Prifti E, Giunti G, Leacche M, Ballo E, Furci B, Salica A, Miraldi F, Mazzesi G, Toscano M
Istituto di Chirurgia del Cuore e dei Grossi Vasi, Università degli Studi di Roma, La Sapienza, Italy.
J Card Surg. 1999 Jul-Aug;14(4):294-300. doi: 10.1111/j.1540-8191.1999.tb00997.x.
The conventional coronary artery bypass procedure that uses venous or arterial conduit for isolated critical stenosis of the left main coronary artery (LMCA) restores a less physiological perfusion of the myocardium and uses an appreciable length of bypass material. Coronary ostial plasty has been described as an alternative surgical technique in proximal obstructive coronary artery disease without calcifications. Here we report 23 patients (15 males and 8 females aged 37-78 years; mean age 57 years) who underwent surgical ostial plasty. Ostial reconstruction with fresh pericardial patch was performed in all patients: 15 patients with LMCA stenosis, 6 patients with right coronary (RC) ostial stenosis, and 2 patients with both RC artery and LMCA stenosis. In seven cases, coronary artery bypass grafting was added for contralateral distal stenosis with a total of five arterial conduits and six venous grafts. One patient died; the ostial plasty and grafts were patent at necropsy. Thallium-201 myocardial scintigraphy under stress at 30 days to 6 months after operation demonstrated good myocardial perfusion in 21 of 22 patients. Coronary angiography at follow-up (49 +/- 8 months) demonstrated good surgical ostial plasty results in 21 of 22 patients and good coronary flow in 19 of 22 patients; angiographic study at mid-term follow-up revealed only one failure of the surgical ostial plasty technique associated with venous graft obstruction. In 2 other patients CABG failure due to venous graft obstruction (1 patient) or distal stenotic lesions of the left coronary artery (1 patient) was noted. The overall successful outcome of the surgical ostial plasty was 22 of 23. We believe that surgical angioplasty of the coronary ostia may be used in the presence of proximal noncalcified obstructive lesions as an alternative technique, which offers a more physiological revascularization; it also spares grafting material and allows subsequent percutaneous transluminal angioplasty or coronary artery bypass surgery.
对于左主干冠状动脉(LMCA)孤立性严重狭窄,采用静脉或动脉管道的传统冠状动脉搭桥手术可恢复心肌的生理性灌注较差,且使用的搭桥材料长度可观。冠状动脉开口成形术已被描述为近端无钙化阻塞性冠状动脉疾病的一种替代手术技术。在此,我们报告23例接受手术开口成形术的患者(15例男性和8例女性,年龄37 - 78岁;平均年龄57岁)。所有患者均采用新鲜心包补片进行开口重建:15例LMCA狭窄患者,6例右冠状动脉(RC)开口狭窄患者,2例RC动脉和LMCA均狭窄患者。7例患者因对侧远端狭窄而加做冠状动脉搭桥术,共使用5根动脉管道和6根静脉移植物。1例患者死亡;尸检时开口成形术和移植物通畅。术后30天至6个月行运动负荷铊-201心肌闪烁显像显示,22例患者中有21例心肌灌注良好。随访(49±8个月)时冠状动脉造影显示,22例患者中有21例手术开口成形术效果良好,22例患者中有19例冠状动脉血流良好;中期随访血管造影研究仅发现1例与静脉移植物阻塞相关的手术开口成形术失败。另外2例患者出现因静脉移植物阻塞导致的冠状动脉搭桥术失败(1例患者)或左冠状动脉远端狭窄病变(1例患者)。手术开口成形术的总体成功结果为23例中的22例。我们认为,冠状动脉开口的手术血管成形术可用于存在近端无钙化阻塞性病变的情况,作为一种替代技术,它能提供更生理性的血运重建;还可节省移植物材料,并允许后续进行经皮腔内血管成形术或冠状动脉搭桥手术。