Kichikawa K, Uchida H, Maeda M, Ide K, Kubota Y, Sakaguchi S, Nishimine K, Higashiura W, Nagata T, Sakaguchi H, Yoshioka T, Ohishi H, Ueda T, Tabayashi N, Taniguchi S
Department of Radiology and Oncoradiology, Nara Medical University, Kashihara, Japan.
J Endovasc Ther. 2000 Jun;7(3):184-91. doi: 10.1177/152660280000700303.
To evaluate the feasibility and efficacy of a newly designed stent-graft placed across the renal arteries for exclusion of abdominal aortic aneurysms (AAAs) with short or tortuous proximal necks.
Among a group of AAA patients treated with endovascular grafting, 5 had tortuous proximal necks and 13 had necks <20 mm (mean 13 mm). In these 18 cases, a 2- to 3-cm uncovered segment of the stent-graft was placed transrenally using a catheter inserted into the renal artery as a guide for graft margin positioning. A newly designed stent-graft was constructed from a custom-made spiral Z-stent covered with a thin-walled Dacron material; the endografts were deployed through 16-F (aortoaortic model) or 18-F sheaths (bifurcated devices). Renal function was assessed by preoperative and postoperative measurement of urea nitrogen and creatinine. Aneurysm exclusion and renal artery patency were evaluated during follow-up using spiral computed tomography and angiography.
The stent-grafts were correctly placed at the intended site in all 18 patients. Renal function was not affected except transiently in 1 patient who developed bilateral renal artery stenoses 24 hours after the procedure; Palmaz stents were deployed in each renal artery to reestablish satisfactory blood flow. Of the 33 renal arteries crossed by the bare stent-graft segment, all were patent over a mean 14-month follow-up (range 7-24), including the patient with Palmaz stents implanted for postprocedural renal stenosis. Complete aneurysm exclusion was maintained in 15 (83%) of 18 patients; proximal leaks persisted in 3 patients, including 2 with severely angled proximal necks.
Transrenal placement of the uncovered leading edge of custom-made spiral Z-stent-based endografts appears feasible and clinically effective in the treatment of AAAs with short or tortuous proximal necks.
评估一种新设计的跨越肾动脉放置的支架型人工血管用于排除近端颈部短或迂曲的腹主动脉瘤(AAA)的可行性和疗效。
在一组接受血管内移植治疗的AAA患者中,5例近端颈部迂曲,13例颈部<20 mm(平均13 mm)。在这18例患者中,以插入肾动脉的导管作为人工血管边缘定位的引导,经肾放置一段2至3 cm无覆膜的支架型人工血管。一种新设计的支架型人工血管由覆盖有薄壁涤纶材料的定制螺旋Z形支架构成;腔内移植物通过16F(主动脉-主动脉模型)或18F鞘管(分叉装置)展开。通过术前和术后测量尿素氮和肌酐来评估肾功能。随访期间使用螺旋计算机断层扫描和血管造影评估动脉瘤排除情况和肾动脉通畅情况。
所有18例患者的支架型人工血管均正确放置在预定部位。除1例患者在术后24小时出现双侧肾动脉狭窄,肾功能有短暂影响外,其余患者肾功能均未受影响;在每个肾动脉中置入Palmaz支架以重建满意的血流。在平均14个月的随访(范围7 - 24个月)中,被裸支架型人工血管段跨越的33条肾动脉均保持通畅,包括因术后肾狭窄植入Palmaz支架的患者。18例患者中有15例(83%)实现了完全动脉瘤排除;3例患者存在近端渗漏,其中2例近端颈部严重成角。
基于定制螺旋Z形支架的腔内移植物无覆膜前缘经肾放置,在治疗近端颈部短或迂曲的AAA方面似乎是可行的且临床有效。