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[治疗“被忽视疾病”的药物:难以下咽的苦药]

[Drugs for 'neglected diseases': a bitter pill].

作者信息

Veeken H, Pécoul B

机构信息

Artsen zonder Grenzen, Medische afdeling, EA Amsterdam.

出版信息

Ned Tijdschr Geneeskd. 2000 Jun 24;144(26):1253-6.

Abstract

Neglected diseases are diseases restricted to poor areas; diseases for which there exist no commercial incentives to invest in the development of new treatments. Patients suffering from these diseases often have no access to essential drugs; this can be a matter of life and death. Lack of research and patent protection play a crucial role. Both are cost driven; greed in the West curtails the availability of life-saving drugs for all. Treatment options for trypanosomiasis and visceral leishmaniasis are lacking. It is recommended that drugs for the treatment of 'neglected diseases' be developed via a centralised, public approach that is not based on profit, rather than leaving it to free enterprise.

摘要

被忽视的疾病是局限于贫困地区的疾病;对于这些疾病,不存在投资开发新疗法的商业激励因素。患有这些疾病的患者往往无法获得基本药物;这可能是生死攸关的问题。缺乏研究和专利保护起到了关键作用。两者都是由成本驱动的;西方的贪婪减少了所有人获得救命药物的机会。治疗锥虫病和内脏利什曼病的选择匮乏。建议通过一种不基于利润的集中式公共方法来开发治疗“被忽视疾病”的药物,而不是将其留给自由企业。

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