Lüke C, Dietlein T, Jacobi P, Konen W, Krieglstein G K
Department of Ophthalmology, University of Cologne, Germany.
Cornea. 2000 Jul;19(4):556-7. doi: 10.1097/00003226-200007000-00030.
Viscocanalostomy in accordance with Stegmann's technique is a new surgical option in the treatment of glaucoma. There are few reports available describing the specific complications of viscocanalostomy. We report a case of intracorneal inclusion of high-molecular-weight sodium hyaluronate following viscocanalostomy.
A 66-year-old man with uncontrolled primary open angle glaucoma of his right eye and a history of argon laser trabeculoplasty underwent viscocanalostomy in accordance with Stegmann's technique. During the filling of Schlemm's canal, a limited lysis of Descemet's membrane advanced centrally in the clear cornea adjacent to the site of canalostomy forming an intracorneal bubble of high-molecular-weight sodium hyaluronate. Postsurgical slit-lamp biomicroscopy showed an intracorneal clear bubble within the corneal periphery without evidence of adjacent corneal edema and with no contact between the corneal endothelium and the iris. Follow-up examinations determined that the appearance of the corneal inclusion, essentially, was unchanged, with only a slight tendency of resorption. No signs of corneal scarring or endothelial decompensation could be noted.
To date, we could not determine a significant corneal damage in conjunction with the described complication. However, it is difficult to predict the long-term clinical course of our patient. Corneal decompensation as a result of possible endothelial toxicity of high-molecular weight sodium hyaluronate as well as spontaneous absorption seem possible.
按照施特格曼技术进行的粘小管切开术是治疗青光眼的一种新的手术选择。关于粘小管切开术具体并发症的报道很少。我们报告一例粘小管切开术后高分子量透明质酸钠角膜内包埋的病例。
一名66岁男性,右眼原发性开角型青光眼控制不佳,有氩激光小梁成形术病史,按照施特格曼技术接受了粘小管切开术。在向施莱姆管填充时,在靠近管切开部位的透明角膜中央,后弹力层出现局限性溶解,形成一个高分子量透明质酸钠角膜内气泡。术后裂隙灯生物显微镜检查显示角膜周边有一个角膜内透明气泡,无相邻角膜水肿迹象,角膜内皮与虹膜无接触。随访检查确定角膜内包埋物的外观基本未变,仅有轻微吸收倾向。未发现角膜瘢痕或内皮失代偿迹象。
迄今为止,我们无法确定所述并发症会导致明显的角膜损伤。然而,很难预测我们患者的长期临床病程。高分子量透明质酸钠可能的内皮毒性以及自发吸收导致角膜失代偿似乎是有可能的。