Suppr超能文献

氟尿嘧啶用于3期-4期治疗

[Use of ftorafur for the treatment of 3d-4th stage].

作者信息

Plaude R K, Osman V I, Tabachnik B I, Purinia I Zh, Gutman E Kh

出版信息

Vopr Onkol. 1975;21(3):44-7.

PMID:1093324
Abstract

To treat ovarian cancer of stage III-IV the authors have used an antimetabolite-fluorafur. A total dosage of 17-23 g. "marked improvement" was noted in 15 patients, "insignificant improvement" - in 9, there was no improvement in one case. It was found that the level of FSH excretion was reduced twice under the influence of fluorafur, the greater decrease corresponding to a better clinical effect. The drug used in doses applied by the authors, proved to be nontoxic.

摘要

为治疗III - IV期卵巢癌,作者使用了抗代谢药物氟尿嘧啶。总剂量为17 - 23克。15例患者出现“明显改善”,9例“改善不明显”,1例无改善。结果发现,在氟尿嘧啶的影响下,促卵泡激素排泄水平降低了一半,降低幅度越大,临床效果越好。作者使用的剂量证明该药物无毒。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验