Kuzuya M, Endo H, Umegaki H, Nakao M, Niwa T, Kumagai T, Ushida Y, Nabeshima T, Iguchi A
Department of Geriatrics, Nagoya University Graduate School of Medicine.
Nihon Ronen Igakkai Zasshi. 2000 May;37(5):363-70. doi: 10.3143/geriatrics.37.363.
Poor medication compliance is a major issue in the health care of older patients. To identify risk factors for medication noncompliance in the elderly, inpatients aged 65 years and older at Nagoya University Hospital and at Chubu National Hospital underwent a comprehensive geriatric assessment and tests for the assessment of medication compliance. The dependency of medication assistance by a caregiver is associated with low physical function activity, cognitive impairment, depression and communication inability. Medication noncompliance was not associated with the score of any component of comprehensive geriatric assessment. There was a good relationship between patient's knowledge of medications and the frequency of dosage interval, both of which were associated with the score of instrumental ADL, cognitive function and communication ability. The knowledge was also associated with the medication compliance at Nagoya University Hospital but not at Chubu National Hospital. These results may suggest that the elderly patient's understanding of a medication regimen is important but that other factors are also required to maintain their treatment regimen.
用药依从性差是老年患者医疗保健中的一个主要问题。为了确定老年人用药不依从的风险因素，名古屋大学医院和中部国立医院的65岁及以上住院患者接受了全面的老年医学评估以及用药依从性评估测试。护理人员对用药协助的依赖性与身体功能活动低下、认知障碍、抑郁和沟通障碍有关。用药不依从与全面老年医学评估的任何组成部分的得分均无关联。患者对药物的了解与给药间隔频率之间存在良好的关系，这两者均与工具性日常生活活动能力、认知功能和沟通能力得分相关。在名古屋大学医院，这种了解也与用药依从性相关，但在中部国立医院则不然。这些结果可能表明，老年患者对药物治疗方案的理解很重要，但维持其治疗方案还需要其他因素。
