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[匈牙利与西方发达国家急性冠状动脉综合征药物治疗模式的比较]

[Comparison of patterns of drug therapy in Hungary and in developed Western countries for acute coronary syndromes].

作者信息

Keltai M

机构信息

Altalános Orvostudományi Kar, Kardiológiai Tanszék, Semmelweis Egyetem, Budapest.

出版信息

Orv Hetil. 2000 Jun 25;141(26):1449-53.

Abstract

Analysis of the data of international multicentric clinical pharmacology trials disclosed that the Hungarian (and Eastern European) patients are more sick, than their western counterparts. The drug prescription habits in Hungary are close to that of international standards. The Hungarian doctors order more nitrates, anticoagulants and ACE inhibitors, but less cholesterol-lowering medication than in other countries. The door-to-needle time in Hungarian patients scheduled for thrombolysis was shorter than the mean. The high price of certain thrombolytic medications prevents Hungarian hospital's doctors to use optimal thrombolytic therapy. The high price of statins in Hungary relative to that of other medications for secondary prevention and to the average per capita income is one of the possible causes that this class of medication is used less frequently in Hungary than in Western Europe. This fact may prevent the decrease of cardiovascular morbidity and mortality on the long-term.

摘要

对国际多中心临床药理学试验数据的分析表明,匈牙利(及东欧)患者比西方患者病情更严重。匈牙利的药物处方习惯接近国际标准。匈牙利医生开具的硝酸盐类、抗凝剂和血管紧张素转换酶抑制剂比其他国家多,但降胆固醇药物比其他国家少。计划进行溶栓治疗的匈牙利患者从就诊到用药的时间短于平均水平。某些溶栓药物价格高昂,阻碍了匈牙利医院的医生采用最佳溶栓疗法。与其他用于二级预防的药物以及人均收入相比,匈牙利他汀类药物价格高昂,这可能是这类药物在匈牙利的使用频率低于西欧的原因之一。这一事实可能会长期阻碍心血管疾病发病率和死亡率的降低。

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