Gentry D, Li T, Rosenberg M, McDevitt D
SmithKline Beecham Pharmaceuticals, Collegeville, Pennsylvania 19426, USA.
J Bacteriol. 2000 Sep;182(17):4995-7. doi: 10.1128/JB.182.17.4995-4997.2000.
The stringent response in Staphylococcus aureus is mediated by the nucleotide guanosine pentaphosphate, whose synthesis is catalyzed by the product of the rel gene. We report here that the rel gene is essential for the in vitro growth of S. aureus, distinguishing it from all other bacteria tested for this requirement.
金黄色葡萄球菌中的严谨反应由核苷酸鸟苷五磷酸介导,其合成由rel基因的产物催化。我们在此报告,rel基因对于金黄色葡萄球菌的体外生长至关重要,这使其与所有其他测试过此需求的细菌有所不同。