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胸膜腔积脓的治疗

Treatment of pleural empyema.

作者信息

Chan P W, Crawford O, Wallis C, Dinwiddie R

机构信息

Respiratory Unit, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.

出版信息

J Paediatr Child Health. 2000 Aug;36(4):375-7. doi: 10.1046/j.1440-1754.2000.00525.x.

Abstract

OBJECTIVE

To determine the clinical presentation and treatment strategies for children admitted with pleural empyema.

METHODOLOGY

Retrospective review of medical and radiological records of 54 patients admitted with pleural empyema between January 1989 and April 1997.

RESULTS

Fever (98%), cough (83%), chest pain (38%), clinical cyanosis (17%) and abdominal pain (16%) were common clinical features. The causative organism was identified in 17 patients (31%). Intravenous antibiotics were given for a mean of 18. 2 +/- 7.5 days. Forty-seven (87%) patients had closed chest tube drainage and 21(39%) patients underwent decortication for unsatisfactory response to medical treatment. The chest tube insertion was more likely to be delayed in patients who required decortication, although the difference was not significant (8.1 +/- 5.4 vs 6.3 +/- 5.2 days of illness, P = 0.67). All patients were discharged well, with almost complete resolution of the chest radiograph at 6 months.

CONCLUSIONS

Intensive medical management with adequate chest tube drainage and appropriate antibiotics will result in full resolution for most patients. Surgical intervention is important in patients who fail to receive adequate treatment early in the disease.

摘要

目的

确定因胸膜腔积脓入院儿童的临床表现及治疗策略。

方法

回顾性分析1989年1月至1997年4月间因胸膜腔积脓入院的54例患者的病历及放射学检查记录。

结果

常见临床表现为发热(98%)、咳嗽(83%)、胸痛(38%)、临床发绀(17%)及腹痛(16%)。17例患者(31%)明确了病原体。静脉使用抗生素的平均时间为18.2±7.5天。47例(87%)患者行胸腔闭式引流,21例(39%)患者因药物治疗效果不佳接受了胸膜剥脱术。尽管差异无统计学意义(发病至置管时间分别为8.1±5.4天和6.3±5.2天,P = 0.67),但需要行胸膜剥脱术的患者胸腔置管更可能延迟。所有患者均康复出院,6个月时胸部X线片几乎完全恢复正常。

结论

强化内科治疗、充分胸腔闭式引流及合理使用抗生素可使大多数患者完全康复。对于疾病早期未得到充分治疗的患者,手术干预很重要。

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