[脑脊髓膜隐球菌病。免疫抑制治疗在肾移植患者中的诱发作用]

[Cerebromeningeal cryptococcosis. Predisposing role of immunosuppressive therapy in patients with kidney transplants].

作者信息

Lissoir F G, Laterre E C, Vandepitte J, Blaton H, Yourassowsky E, Schouttens E

出版信息

Pathol Biol (Paris). 1975 Mar;23(3):211-8.

Abstract

Disseminated cryptococcal infection is described in eight patients, seven of them with verified meningeal involvement. Six of the eight patients were recipients of a renal homograft and submitted to the classical immunosuppressive treatment. Consideration is given to predisposing factors and to problems in the clinical, biological and mycological diagnosis. Some comments are presented on the often disappointing results of antifungal therapy of cryptococcal meningitis.

摘要

本文描述了8例播散性隐球菌感染患者，其中7例经证实有脑膜受累。这8例患者中有6例接受了同种异体肾移植，并接受了经典的免疫抑制治疗。文中考虑了易感因素以及临床、生物学和真菌学诊断方面的问题。同时对隐球菌性脑膜炎抗真菌治疗常常令人失望的结果进行了一些评论。