Mayer D J, Price D D, Becker D P, Young H F
J Neurosurg. 1975 Oct;43(4):445-7. doi: 10.3171/jns.1975.43.4.0445.
A sensitive quantitative index for predicting optimal electrode position in percutaneous anterolateral cordotomy was determined by electrical stimulation through the lesioning electrode. If the threshold for pain elicited by the stimulation electrode was less than 300 muA, a 5-sec radiofrequency lesion of 50 mA would produce complete contralateral analgesia with no weakness. When the pain threshold exceeded 300 muA, incomplete or no analgesia would result with the standard single lesion. The results further suggested that the fibers in the anterolateral quadrant that transmit pain are discretely rather than diffusely localized.
通过损伤电极进行电刺激,确定了一种用于预测经皮前外侧脊髓切开术中最佳电极位置的敏感定量指标。如果刺激电极引发疼痛的阈值小于300微安,50毫安的5秒射频损伤将产生完全的对侧镇痛且无无力现象。当疼痛阈值超过300微安时,标准的单次损伤将导致不完全或无镇痛效果。结果进一步表明,前外侧象限中传递疼痛的纤维是离散分布而非弥散分布的。