面对抗生素耐药性时治疗慢性支气管炎急性加重期

Treating acute exacerbations of chronic bronchitis in the face of antibiotic resistance.

作者信息

Adams S G, Anzueto A

机构信息

Department of Medicine, University of Texas Health Science Center at San Antonio, USA.

出版信息

Cleve Clin J Med. 2000 Sep;67(9):625-8, 631-3. doi: 10.3949/ccjm.67.9.625.

DOI:10.3949/ccjm.67.9.625

PMID:10992620

Abstract

Antibiotics can be effective against acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease, but with bacterial resistance to multiple antibiotics increasing worldwide, appropriate antibiotic selection is critical. Categorizing patients with acute exacerbations according to age, number of exacerbations per year, disease severity, degree of pulmonary impairment, and presence of comorbid conditions helps to direct therapy.

摘要

抗生素对慢性支气管炎和慢性阻塞性肺疾病的急性加重期可能有效，但随着全球范围内细菌对多种抗生素的耐药性增加，选择合适的抗生素至关重要。根据年龄、每年加重次数、疾病严重程度、肺功能损害程度以及合并症的存在情况对急性加重期患者进行分类有助于指导治疗。